Author: Sander Timmer

PhD student in computational genetics at Cambridge University and EMBL-European Bioinformatics Institute
Biology Circle (Profiles Only)

Biology Circle (Profiles Only)

Reshared post from +Science on Google+

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10 great articles by +New Scientist about human evolutionary questions.

10 great articles by +New Scientist about human evolutionary questions.

10 great articles by +New Scientist about human evolutionary questions.

10 biggest puzzles of human evolution – New Scientist
We are the ape that stood on two feet, lost its fur and crossed the globe – but why? New Scientist explores these and other enduring riddles of our past

Genome wide association study for personality where they studied the following QTLs:…

Genome wide association study for personality where they studied the following QTLs:…

Genome wide association study for personality where they studied the following QTLs: Neuroticism, Extraversion, Openness to Experience, Agreeableness and Conscientiousness.

+Mikhail Spivakov what are your alleles for rs1477268, rs2032794 and rs2576037? 😉

http://goo.gl/J999U

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http://goo.gl/J999U

Taking invisibility to the next level!

Taking invisibility to the next level!

Taking invisibility to the next level!

Reshared post from +Nature News & Comment

Physicists have already unveiled invisibility cloaks that can hide objects from light, sound, seismic and even water waves. Now researchers report a cloak that can hide objects from static magnetic fields. This 'antimagnet' could have medical applications, but might also subvert airport security.

‘Antimagnet’ renders magnets invisible
Magnetic cloak could bring medical benefits — and security risks.

Aspirin as a cancer prevention method

Aspirin as a cancer prevention method

In a study where they followed patients for several years they found drastic reduced risk for several cancers indicating that maybe an aspirin a day could be used as a prevention drug. Most likely the aspirin is active at early stage of cancer as the best improvement is only found after 5 years of low daily aspirin intake.

"In The Lancet, Peter Rothwell and colleagues1 report additional data supporting the hope that daily aspirin can ward off a panoply of cancers. Aspirin's role in reducing risk of vascular events is well established, although which risk factor profiles derive net benefit remain controversial.2 The strongest proof of aspirin's antineoplastic effect has been in colorectal tumours. Several epidemiological studies,3 randomised controlled trials of colon polyp recurrence,4 and randomised trials in patients with hereditary colorectal cancer syndromes [5] and [6] have shown that aspirin reduces incidence of colorectal neoplasia. In long-term follow-up of participants in five randomised trials of cardiovascular prevention, Rothwell and colleagues previously reported that daily aspirin at any dose reduced risk of colorectal cancer by 24% and of associated mortality by 35% after a delay of 8–10 years.7"

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Are we ready to recommend aspirin for cancer prevention? : The Lancet
Are we ready to recommend aspirin for cancer prevention?. By – Andrew T Chan, Nancy R Cook

Great overview of RNA-seq tool pipelines

Great overview of RNA-seq tool pipelines

Not the most recent paper but still a pretty good starting point for deciding what tool you're going to use in your experiment. Also, things like QA and aligning from this paper can be used when working with other sequencing methods.

Computational methods for transcriptome annotation and quantification using RNA-seq : Nature Methods : Nature Publishing Group
High-throughput RNA sequencing (RNA-seq) promises a comprehensive picture of the transcriptome, allowing for the complete annotation and quantification of all genes and their isoforms across samples. …